Difference between revisions of "Dr. Ethan A. Merritt Laboratory"
From Christoph's Personal Wiki
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*[http://skuld.bmsc.washington.edu/~tlsmd/ TLSMD Server] | *[http://skuld.bmsc.washington.edu/~tlsmd/ TLSMD Server] | ||
*[http://www.sgpp.org/ Structural Genomics of Pathogenic Protozoa] | *[http://www.sgpp.org/ Structural Genomics of Pathogenic Protozoa] | ||
| + | ===Genome projects=== | ||
| + | *[http://www.plasmodb.org/ PlasmoDB] — ''Plasmodium'' spp. | ||
| + | *[http://www.genedb.org/ GeneDB] — ''Trypanosomatids, Entamoeba, Plasmodium'' | ||
| + | *[http://tcruzidb.org/ TcruziDB] — ''T. cruzi'' | ||
| + | *[http://cryptodb.org/ CryptoDB] — ''Cryptosporidium'' | ||
| + | *[http://gmod.mbl.edu/perl/site/giardia GardiaDB] — ''Giardia lamblia'' | ||
| + | *[http://www.toxodb.org/ ToxoDB] — ''Toxoplasma gondii'' | ||
[[Category:Academic Research]] | [[Category:Academic Research]] | ||
Revision as of 23:47, 20 August 2007
The Dr. Ethan A. Merritt Laboratory
Contents
Research topics
- structure-based drug design
- high-resolution protein crystallography
MSGPP
I am part of the Medical Structural Genomics of Pathogenic Protozoa Consortium (MSGPP). The pathogenic protozoa we study include the following:
Trypanosoma
- Trypanosoma cruzi
- Chagas' Disease
- Trypanosoma brucei
- Sleeping Sickness
- Leishmania spp.
- Leishmaniasis
Apicomplexa
- Plasmodium falciparum
- Malaria
- Plasmodium vivax
- Malaria
- Toxoplasma gondii
- Toxoplasmosis
Others
- Entamoeba histolytica
- Amoebiasis
- Giardia lamblia
- Giardiasis
- Cryptosporidium parvum
- Cryptosporidiosis
References
Further reading
- Merritt EA, Zhang Z, Pickens JC, Ahn M, Hol WGJ, Fan E (2002). Characterization and crystal structure of a high-affinity pentavalent receptor-binding inhibitor for cholera toxin and E. coli heat-labile enterotoxin. JACS, 124:8818-8824.
- Fan E, Merritt EA, Verlinde CLMJ, Hol WGJ (2000). AB5 toxins: structures and inhibitor design. Current Opinion in Structural Biology, 10:680-686.
- Merritt EA (1999). Comparing anisotropic displacement parameters in protein structures. Acta Cryst, D55:1997-2004.
- Merritt EA (1999). Expanding the model: anisotropic displacement parameters in protein structure refinement. Acta Cryst, D55:1109-1117.
See also
- TLSMD
- Python Macromolecular Library (mmLib)
