Difference between revisions of "Molecular Evolution (academic course)"
(→External links) |
|||
| Line 2: | Line 2: | ||
==Overview== | ==Overview== | ||
| − | === | + | === Objectives === |
To provide the student with broad knowledge in the field of molecular evolution (i.e., the evolution of DNA, RNA, and proteins), and with in-depth knowledge of model-based methods for phylogenetic tree reconstruction and hypothesis testing in an evolutionary context. Although the study of molecular evolution does require a certain level of mathematical understanding, this course has been designed to attract a diverse range of students. | To provide the student with broad knowledge in the field of molecular evolution (i.e., the evolution of DNA, RNA, and proteins), and with in-depth knowledge of model-based methods for phylogenetic tree reconstruction and hypothesis testing in an evolutionary context. Although the study of molecular evolution does require a certain level of mathematical understanding, this course has been designed to attract a diverse range of students. | ||
| − | ===Content=== | + | === Content === |
Brief introduction to evolutionary theory and population genetics. Mechanisms of molecular evolution. Models of DNA and protein substitution. Reconstruction of phylogenetic trees using distance based methods, parsimony, maximum likelihood, and Bayesian | Brief introduction to evolutionary theory and population genetics. Mechanisms of molecular evolution. Models of DNA and protein substitution. Reconstruction of phylogenetic trees using distance based methods, parsimony, maximum likelihood, and Bayesian | ||
| Line 13: | Line 13: | ||
The student will acquire practical experience in the use of computational methods by analyzing sequences from the scientific literature. | The student will acquire practical experience in the use of computational methods by analyzing sequences from the scientific literature. | ||
| − | === | + | === Details === |
| − | * '''''[[Inferring Phylogenies]]''''', Joseph Felsenstein, Sinauer Associates, Inc. (2003) | + | * Textbook: '''''[[Inferring Phylogenies]]''''', Joseph Felsenstein, Sinauer Associates, Inc. (2003) |
| − | + | * Professor: Dr. Anders Gorm Pedersen | |
| − | + | ||
| − | * Professor: Anders Gorm Pedersen | + | |
| − | + | ||
* Home Page: http://www.cbs.dtu.dk/courses/27615.mol/ | * Home Page: http://www.cbs.dtu.dk/courses/27615.mol/ | ||
* Semester: Spring 2006 (8 February 2006 — 3 May 2006; Wed; 13:00 - 17:00) | * Semester: Spring 2006 (8 February 2006 — 3 May 2006; Wed; 13:00 - 17:00) | ||
| − | ===Key words=== | + | === Key words === |
Molecular evolution, DNA, RNA, proteins | Molecular evolution, DNA, RNA, proteins | ||
| + | |||
| + | == See also == | ||
| + | * [[:Category:Phylogenetics|Phylogenetics]] | ||
== External links == | == External links == | ||
Latest revision as of 00:09, 9 August 2006
Content is archived here for educational purposes only.
Contents
Overview
Objectives
To provide the student with broad knowledge in the field of molecular evolution (i.e., the evolution of DNA, RNA, and proteins), and with in-depth knowledge of model-based methods for phylogenetic tree reconstruction and hypothesis testing in an evolutionary context. Although the study of molecular evolution does require a certain level of mathematical understanding, this course has been designed to attract a diverse range of students.
Content
Brief introduction to evolutionary theory and population genetics. Mechanisms of molecular evolution. Models of DNA and protein substitution. Reconstruction of phylogenetic trees using distance based methods, parsimony, maximum likelihood, and Bayesian techniques. Advanced models of nucleotide substitution (gamma-distributed mutation rates, molecular clock models, codon models and analysis of selective pressure). Statistical analysis of biological hypotheses (likelihood ratio tests, parametric bootstrapping, Bayesian statistics).
The student will acquire practical experience in the use of computational methods by analyzing sequences from the scientific literature.
Details
- Textbook: Inferring Phylogenies, Joseph Felsenstein, Sinauer Associates, Inc. (2003)
- Professor: Dr. Anders Gorm Pedersen
- Home Page: http://www.cbs.dtu.dk/courses/27615.mol/
- Semester: Spring 2006 (8 February 2006 — 3 May 2006; Wed; 13:00 - 17:00)
Key words
Molecular evolution, DNA, RNA, proteins
