FastContact

FastContact is a rapid estimate of contact and binding free energies for protein-protein complex structures. The programme was written in Fortran by Carlos J. Camacho and Chao Zhang at the Department of Computational Biology, University of Pittsburgh Pittsburgh, PA.

A web server was setup by Christoph Champ in July 2005 for running this programme.

The executable and full documentation is freely available at http://structure.pitt.edu/software/FastContact

Keywords

docking, protein interactions, scoring, complex structure, binding mechanism, recognition, desolvation, free energy

References

• Camacho CJ and Zhang C (2005). FastContact: rapid estimate of contact and binding free energies. Bioinformatics, 21(10):2534-6.
• Camacho CJ, Ma H, and Champ PC (2006). Scoring a diverse set of high-quality docked conformations: A metascore based on electrostatic and desolvation interactions. Proteins, 63(4):868-77.

External links

• FastContact binaries — available for download
• FastContact Server