Difference between revisions of "DNA-binding domain"

Latest revision as of 01:50, 3 May 2008

A DNA-binding domain (DBD) includes any protein motif that binds to double- or single-stranded DNA with affinity to a specific sequence or set thereof or a general affinity to DNA.^[1]

Types of DNA-binding domains

• Helix-turn-helix
• Zinc finger
• Leucine zipper
• Winged helix
• Winged helix turn helix
• Helix-loop-helix

Unusual DNA binding domains

• Immunoglobulin fold
• B3 domain

References

1. ↑ Lilley DMJ (1995). "DNA-protein: structural interactions". IRL Press at Oxford University Press, Oxford. ISBN 0-19-963453-X.

External links

• DBD database of predicted transcription factors — uses a curated set of DNA-binding domains to predict transcription factors in all completely sequenced genomes
• Table of DNA-binding motifs
• wikipedia:DNA-binding domain