Difference between revisions of "Molecular Evolution (academic course)"

From Christoph's Personal Wiki
Jump to: navigation, search
(Started article)
 
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
 +
{{FairUse}}
 
==Overview==
 
==Overview==
  
===Aim/objectives===
+
=== Objectives ===
  
 
To provide the student with broad knowledge in the field of molecular evolution (i.e., the evolution of DNA, RNA, and proteins), and with in-depth knowledge of model-based methods for phylogenetic tree reconstruction and hypothesis testing in an evolutionary context. Although the study of molecular evolution does require a certain level of mathematical understanding, this course has been designed to attract a diverse range of students.
 
To provide the student with broad knowledge in the field of molecular evolution (i.e., the evolution of DNA, RNA, and proteins), and with in-depth knowledge of model-based methods for phylogenetic tree reconstruction and hypothesis testing in an evolutionary context. Although the study of molecular evolution does require a certain level of mathematical understanding, this course has been designed to attract a diverse range of students.
  
===Content===
+
=== Content ===
  
 
Brief introduction to evolutionary theory and population genetics. Mechanisms of molecular evolution. Models of DNA and protein substitution. Reconstruction of phylogenetic trees using distance based methods, parsimony, maximum likelihood, and Bayesian
 
Brief introduction to evolutionary theory and population genetics. Mechanisms of molecular evolution. Models of DNA and protein substitution. Reconstruction of phylogenetic trees using distance based methods, parsimony, maximum likelihood, and Bayesian
Line 12: Line 13:
 
The student will acquire practical experience in the use of computational methods by analyzing sequences from the scientific literature.
 
The student will acquire practical experience in the use of computational methods by analyzing sequences from the scientific literature.
  
===Contact===
+
=== Details ===
* Professor: Anders Gorm Pedersen, build. 208, room 017, (+45) 4525 2484, gorm@cbs.dtu.dk
+
* Textbook: '''''[[Inferring Phylogenies]]''''', Joseph Felsenstein, Sinauer Associates, Inc. (2003)
* Department: 27 BioCentrum-DTU
+
* Professor: Dr. Anders Gorm Pedersen
 
* Home Page: http://www.cbs.dtu.dk/courses/27615.mol/
 
* Home Page: http://www.cbs.dtu.dk/courses/27615.mol/
 +
* Semester: Spring 2006 (8 February 2006 — 3 May 2006; Wed; 13:00 - 17:00)
  
===Key words===
+
=== Key words ===
 
Molecular evolution, DNA, RNA, proteins
 
Molecular evolution, DNA, RNA, proteins
 +
 +
== See also ==
 +
* [[:Category:Phylogenetics|Phylogenetics]]
 +
 +
== External links ==
 +
* [http://en.wikipedia.org/wiki/Molecular_evolution Wikipedia article on '''Melecular evolution''']
  
 
[[Category:Academic Courses]]
 
[[Category:Academic Courses]]

Latest revision as of 00:09, 9 August 2006

Content is archived here for educational purposes only.

Overview

Objectives

To provide the student with broad knowledge in the field of molecular evolution (i.e., the evolution of DNA, RNA, and proteins), and with in-depth knowledge of model-based methods for phylogenetic tree reconstruction and hypothesis testing in an evolutionary context. Although the study of molecular evolution does require a certain level of mathematical understanding, this course has been designed to attract a diverse range of students.

Content

Brief introduction to evolutionary theory and population genetics. Mechanisms of molecular evolution. Models of DNA and protein substitution. Reconstruction of phylogenetic trees using distance based methods, parsimony, maximum likelihood, and Bayesian techniques. Advanced models of nucleotide substitution (gamma-distributed mutation rates, molecular clock models, codon models and analysis of selective pressure). Statistical analysis of biological hypotheses (likelihood ratio tests, parametric bootstrapping, Bayesian statistics).

The student will acquire practical experience in the use of computational methods by analyzing sequences from the scientific literature.

Details

Key words

Molecular evolution, DNA, RNA, proteins

See also

External links