Biophysics (academic course)
Biophysics was a year-long academic course I took during my undergraduate years at Oregon State University. It was a professional course sequence covering basic principles of biological systems and biological phenomena, and the methods to study these, using concepts derived from mathematics and physics.
- Professors: Dr. P. Shing Ho, Dr. Victor Hsu, and Dr. P. Andrew Karplus .
- Textbook: Physical Biochemistry, Kensal E. van Holde, W. Curtis Johnson, and P. Shing Ho, Prentice Hall, New Jersey (1998).
The course was divided into three terms.
Biophysics I (by Dr. Ho)
Molecular Thermodynamics: Basic concepts of biological macromolecules, and molecular thermodynamics and statistical mechanics methods for understanding macromolecular structure.
Keywords: Biological Macromolecules (Interactions, Environments, Symmetry, Structure), Molecular Thermodynamics, Statistical Thermodynamics (Structural Transitions in Polypeptides and Proteins, Structural Transitions in Polynucleotides and DNA, Nonregular Structures)
Biophysics II (by Dr. Hsu)
Spectroscopy: Quantum mechanics and spectroscopy, absorption and emission spectroscopy, linear and circular dichroism, and nuclear magnetic resonance spectroscopy.
Keywords: Quantum Mechanics, Spectroscopy (Absorption, Linear and Circular Dichroism, Emisson, NMR).
Biophysics III (by Dr. Karplus)
Macromolecular Structure and Behavior: Methods for determining macromolecular structure (X-ray diffraction, NMR); behavior of macromolecules in solution.
Keywords: Macromolecular Structure Determination, X-ray Crystallography, Hydrogen Exchange (Dynamics, Thermodynamics, Structure), Atomic Force Microscopy, Mass Spectroscopy, Protein Folding.